Your skin stings when you cleanse, flares red in cold weather, and reacts to everything. The Bioderma Créaline Défensive Serum rebuilds your barrier so you can finally tolerate the products you love. Three weeks in, your skin stops acting out.

Key Benefits

  • Shields against daily aggressors: protects your barrier from pollution, temperature swings, and indoor heating
  • Calms tightness and sting: soothes reactive, uncomfortable skin within the first application
  • Hydrates without weight: squalane and glycerin replenish moisture while feeling invisible
  • Reduces future flare-ups: strengthens your skin's defenses so reactions happen less often over time
  • Supports your microbiome: Bioderma's ecobiology approach keeps good bacteria balanced
  • Safe for hypersensitive types: hypoallergenic, fragrance-free, tested on reactive skin

Key Ingredients

Carnosine: a peptide that shields against free radicals and slows visible aging triggered by pollution and UV exposure. Hydrolyzed Hyaluronic Acid: a low-weight form that penetrates deeper to plump skin from within and hold moisture for hours. Squalane: a plant-based lipid that mimics your skin's natural oils, sealing in hydration without clogging pores. Salvia Miltiorrhiza Root Extract: a botanical active that soothes inflammation and calms redness. Palmitoyl Tetrapeptide-10: a peptide that strengthens the barrier by promoting collagen synthesis and ceramide production.

Shop all Bioderma products at Paris Pharmacy.

Bioderma Créaline Défensive Serum

Regular price $60.99
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Your skin stings when you cleanse, flares red in cold weather, and reacts to everything. The Bioderma Créaline Défensive Serum rebuilds your barrier so you can finally tolerate the products you love. Three weeks in, your skin stops acting out.

Key Benefits

  • Shields against daily aggressors: protects your barrier from pollution, temperature swings, and indoor heating
  • Calms tightness and sting: soothes reactive, uncomfortable skin within the first application
  • Hydrates without weight: squalane and glycerin replenish moisture while feeling invisible
  • Reduces future flare-ups: strengthens your skin's defenses so reactions happen less often over time
  • Supports your microbiome: Bioderma's ecobiology approach keeps good bacteria balanced
  • Safe for hypersensitive types: hypoallergenic, fragrance-free, tested on reactive skin

Key Ingredients

Carnosine: a peptide that shields against free radicals and slows visible aging triggered by pollution and UV exposure. Hydrolyzed Hyaluronic Acid: a low-weight form that penetrates deeper to plump skin from within and hold moisture for hours. Squalane: a plant-based lipid that mimics your skin's natural oils, sealing in hydration without clogging pores. Salvia Miltiorrhiza Root Extract: a botanical active that soothes inflammation and calms redness. Palmitoyl Tetrapeptide-10: a peptide that strengthens the barrier by promoting collagen synthesis and ceramide production.

Shop all Bioderma products at Paris Pharmacy.

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Born in Southern California. Delivered by our trusted USA-based brand partners. Every piece is handpicked for the woman who moves through the world with intention and grace. Ask me anything — I am always here to help. 🖤